Synthesis of new Pd(NHC)-PEPPSI type complexes as catalysts toward C-C cross-coupling reactions

Nawaz Z., GÜRBÜZ N., Zafar M. N., Özdemir N., Habib U., Jan K., ...More

JOURNAL OF MOLECULAR STRUCTURE, vol.1243, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 1243
  • Publication Date: 2021
  • Doi Number: 10.1016/j.molstruc.2021.130883
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core, INSPEC
  • Keywords: N-heterocyclic carbene, Palladium-PEPPSI complexes, Suzuki-Miyaura coupling, Mizoroki-Heck coupling, Sonogashira coupling, N-HETEROCYCLIC CARBENES, PALLADIUM-PEPPSI COMPLEXES, ARYL CHLORIDES, ROOM-TEMPERATURE, NHC NHC, LIGANDS, PRECATALYST, REACTIVITY, HECK, PHENYLENE
  • Ondokuz Mayıs University Affiliated: Yes


The goal of our research is to synthesis homogeneous catalysts, for which we take start from two novel precursors of 1-(3-methyloxetane-3-yl)benzimidazole and 5,6-dimethyl-1-((3-methyloxetane3-yl)benzimidazole. A series of ligands containing 1,3-disubstituted benzimidazolium salts were synthesized from the corresponding precursors to form N-heterocyclic carbene (NHC) ligands. Furthermore, four new Pd(NHC)-PEPPSI type complexes were synthesized from these ligands. The structure elucidation of all the synthesized ligands, and complexes was confirmed by various spectroscopic techniques such as NMR, FT-IR. The compounds 1b, 2b, 3a, 3d were confirmed by the X-ray technique. All these complexes were found significantly active as catalysts toward the C-C cross-coupling reaction. (c) 2021 Elsevier B.V. All rights reserved.