Antimicrobial activity of essential oil components and antiproliferative activity of trans-tiliroside compound from an endemic desert species Thymelaea microphylla Coss. et Dur.
Research Journal of Pharmaceutical, Biological and Chemical Sciences, cilt.6, sa.2, ss.671-676, 2015 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 6 Sayı: 2
- Basım Tarihi: 2015
- Dergi Adı: Research Journal of Pharmaceutical, Biological and Chemical Sciences
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.671-676
- Anahtar Kelimeler: Antimicrobial activity, Antiproliferative activity, Essential oil, T .microphylla, Trans-tiliroside
- Ondokuz Mayıs Üniversitesi Adresli: Hayır
Özet
Essential oil components of the aerial parts of Thymelaea microphylla was subjected to evaluate the antimicrobial activity by disc diffusion method and tested against Gram-positive and Gram-negative bacteria and showed a high antibacterial activity against E.coli and Staphylococcus aureus at 2000μg /ml. The antiproliferative activity of fraction (7) from Thymelaea microphylla showed significant inhibitory activity on HeLa cells and moderate antiproliferative activity of trans-tiliroside compound was investigated in vitro on HeLa cells (human uterus carcinoma) activity and C6 cells (rat brain tumor).