Clinical Utility of Objective Tests for Dry Eye Disease: Variability Over Time and Implications for Clinical Trials and Disease Management

Sullivan B. D., Crews L. A., Sonmez B., de la Paz M. F., Comert E., Charoenrook V., ...More

CORNEA, vol.31, no.9, pp.1000-1008, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 9
  • Publication Date: 2012
  • Doi Number: 10.1097/ico.0b013e318242fd60
  • Journal Name: CORNEA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1000-1008
  • Keywords: dry eye disease, tear osmolarity, cyclosporine, Restasis, TearLab, TEAR FILM OSMOLARITY, MODE FRICTIONAL-PROPERTIES, OPHTHALMIC EMULSION, EPITHELIAL-CELLS, DIAGNOSTIC-TESTS, HYPEROSMOLARITY, SYMPTOMS, PRESSURE, EFFICACY, SAFETY
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Purpose: To evaluate the efficacy of commonly used biomarkers in dry eye disease management in a longitudinal observational case series study followed by an interventional study in a subset of subjects treated with cyclosporine A (0.05%).