Statistical Shape Analysis of Subthalamic Nucleus in Patients with Parkinson Disease

Kaya M. O., ÖZTÜRK S., ERCAN İ., Gonen M., EROL F. S., Kocabıçak E.

WORLD NEUROSURGERY, vol.126, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 126
  • Publication Date: 2019
  • Doi Number: 10.1016/j.wneu.2019.02.180
  • Journal Name: WORLD NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Keywords: Deep brain stimulation, Deformation, Parkinson disease, Statistical shape analysis, Subthalamic nucleus, NEURONAL-ACTIVITY
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

OBJECTIVE: Subthalamic nucleus (STN) is the most targeted localization in the treatment of Parkinson disease (PD) with deep brain stimulation. However, no studies have been found in the literature about possible shape changes of STN in the literature. We aimed to investigate possible shape changes in the STN and the relationship between shape changes and disease duration in PD patients by using statistical analysis.