Relationships Between Symmetric Dimethylarginine (SDMA), Blood Urea Nitrogen and Creatinine Levels in Dog


Meral Y., Sayılkan B. U., Özcan Ü., Küllük E., Çenesiz S., Dalğın D.

Turk!sh Journal of Veter!nary Internal Med!c!ne (TJVIM), cilt.3, sa.1, ss.5-9, 2024 (Hakemli Dergi)

Özet

enal failure is a frequently encountered disorder of
the dogs and cats. Blood urea and creatinine levels are the
conventional diagnostic parameters, but elevate only a
!
er
advanced stage, so a signi
"
cant period for the therapy onset
is mislayed. Serum symetric dimethly arginine (SDMA) is a
spesi
"
c and early biomarker of renal insu
#
ciency.
$
e aim of
this study is to investigate the state of relationships between
SDMA, BUN and creatinine levels in dogs. In the present
study, SDMA, BUN and creatinine levels are determined in
50 dogs by ELISA. Obtained results displayed an absence of a
correlation, but also indicated renal insu
#
ciency in 14% of the
dogs which had none related clinical su
%
ering or laboratory
"
nding.
$
is striking ratio displayes the diagnostic e
#
ciency
of SDMA and also emphasizes the requirement of routine
SDMA usage in clinical practice on behalf of early diagnosis,
theurapeutic success, therapy expanses and animal welf