The impact of progesterone supplementation on pregnancy rates after intrauterine insemination in patients developing a single follicle

Güven D., Batioglu A., Sari S., Bakay A.

HUMAN FERTILITY, vol.19, no.2, pp.111-113, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.1080/14647273.2016.1186847
  • Journal Name: HUMAN FERTILITY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.111-113
  • Keywords: Intrauterine insemination, live-birth rates, pregnancy, progesterone, LUTEAL-PHASE SUPPORT, IN-VITRO FERTILIZATION, INTRAMUSCULAR PROGESTERONE, VAGINAL PROGESTERONE, CYCLES, IVF, GEL
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

The objective was to determine whether progesterone support affects pregnancy rates in patients who develop a single follicle. This was a non-randomized prospective controlled study performed on 591 intrauterine insemination (IUI) cycles that developed a single follicle; 337 women received 100mg oral progesterone daily. The pregnancy rate was 24.3%, or 82 out of 337, in the group receiving progesterone support compared with 14.96%, or 254 out of 591, in the group with no progesterone support. IUI luteal phase supplementation with oral progesterone may improve clinical pregnancy rates when begun the day after insemination.