Excessive fluoride intake alters the MMP-2, TIMP-1 and TGF-beta levels of periodontal soft tissues: an experimental study in rabbits

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Lütfioğlu M., Sakallioglu E. E., Sakallioglu U., Gülbahar M. Y., Muğlalı M., Baş Akkor B., ...Daha Fazla

CLINICAL ORAL INVESTIGATIONS, cilt.16, sa.6, ss.1563-1570, 2012 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 16 Sayı: 6
• Basım Tarihi: 2012
• Doi Numarası: 10.1007/s00784-011-0652-6
• Dergi Adı: CLINICAL ORAL INVESTIGATIONS
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.1563-1570
• Anahtar Kelimeler: Excessive fluoride intake, Periodontium, MMP-2, TIMP-1, TGF-beta, CELLS IN-VITRO, MATRIX METALLOPROTEINASES, CHRONIC FLUOROSIS, SODIUM-FLUORIDE, LIPID-PEROXIDATION, CREVICULAR FLUID, EXPRESSION, INHIBITOR, 2ND-GENERATION, BONE
• Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objectives This study evaluated the influence of fluoride on periodontal soft tissues by investigating any alterations in their MMP-2, TIMP-1 and TGF-beta profiles secondary to excessive fluoride intake.