The effect of acute organophosphate intoxication on female rat hippocampus cornu ammonis region pyramidal neuron numbers, biochemistry and morphology

BAŞ, ORHAN; ÇANKAYA, Soner; ENGİNYURT, ÖZGÜR; Aslan, Ali; Uydu, Huseyin; Odaci, Ersan; YILMAZ, ALİ; DEMİR, ADEM; Gul, Tuba

doi:10.1016/j.jchemneu.2019.101652

The effect of acute organophosphate intoxication on female rat hippocampus cornu ammonis region pyramidal neuron numbers, biochemistry and morphology

BAŞ O., ÇANKAYA S., ENGİNYURT Ö., Aslan A., Uydu H. A., Odaci E., ...Daha Fazla

JOURNAL OF CHEMICAL NEUROANATOMY, cilt.100, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 100
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.jchemneu.2019.101652
Dergi Adı: JOURNAL OF CHEMICAL NEUROANATOMY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: Organophosphate, Fenthion, Hippocampus, Stereology, Rat, OXIDATIVE STRESS, LIPID-PEROXIDATION, ELECTROMAGNETIC-FIELD, RESPIRATORY-FAILURE, ANTIOXIDANT ENZYMES, PESTICIDE EXPOSURE, INHIBITION, DAMAGE, NEUROTOXICITY, MECHANISMS
Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: The most commonly used insecticides and pesticides worldwide are organophosphate compounds, chemicals that irreversibly inhibit the cholinesterase enzyme. Acute intoxication with cholinesterase inhibitors is known to cause permanent effects on both the human and rat brains.