Device-associated nosocomial infections in 55 intensive care units of 8 developing countries

Rosenthal V. D., Maki D. G., Salomao R., Alvarez-Moreno C., Mehta Y., Higuera F., ...More

ANNALS OF INTERNAL MEDICINE, vol.145, no.8, pp.582-591, 2006 (SCI-Expanded) identifier identifier


Background: Health care-associated infections from invasive medical devices in the intensive care unit (ICU) are a major threat to patient safety. Most published studies of ICU-acquired infections have come from industrialized western countries. In a Centers for Disease Control and Prevention (CDC) National Nosocomial Infections Surveillance (NNIS) System report, the U.S. pooled mean rates of central venous catheter (CVC)-related bloodstream infections, ventilator-associated pneumonia, and catheter-associated urinary tract infections were 4.0 per 1000 CVC days, 5.4 per 1000 mechanical ventilator days, and 3.9 per Foley catheter days, respectively.