Effect of ranolazine on Tp-e interval, Tp-e/QTc, and P-wave dispersion in patients with stable coronary artery disease

Akçay M., Çoksevim M., Yenercag M.

JOURNAL OF ARRHYTHMIA, cilt.37, sa.4, ss.1015-1022, 2021 (ESCI, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1002/joa3.12549
  • Dergi Adı: JOURNAL OF ARRHYTHMIA
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, EMBASE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.1015-1022
  • Anahtar Kelimeler: coronary artery disease, index of cardiac electrophysiological balance (iCEB), P-wave dispersion, ranolazine, Tp-e interval, CHRONIC ANGINA, ATRIAL, RATIO, REPOLARIZATION, ELEVATION, EVENTS, INDEX, QT
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Introduction: Ranolazine is an antianginal drug and also exhibits antiarrhythmic effect by affecting action potential time, refractory period, and repolarization reserve. We evaluated the effect of ranolazine therapy on myocardial repolarization parameters (Tp-e, QT, QTc intervals, Tp-e/QT, and Tp-e/QTc ratios), index of cardiac electrophysiological balance (iCEB) (QT/QRS, QTc/QRS) and P-wave dispersion (PWD) in patients with stable coronary artery disease (CAD).