The effect of combined treatment of alpha-tocopherol, ascorbic acid, and pyridoxine with NMDA blocker memantine on penicillin-induced epileptiform activity in rats
TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.43, sa.2, ss.245-250, 2013 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 43 Sayı: 2
- Basım Tarihi: 2013
- Doi Numarası: 10.3906/sag-1204-7
- Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.245-250
- Anahtar Kelimeler: Experimental epilepsy, NMDA, memantine, ascorbic acid, pyridoxine, alpha-tocopherol, VITAMIN-E, OXIDATIVE STRESS, KINDLING MODEL, NITRIC-OXIDE, PENTYLENETETRAZOL, SEIZURES
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Aim: To evaluate the effects of coadministration of vitamins alpha-tocopherol, ascorbic acid, and pyridoxine with memantine on a penicillin-induced experimental epilepsy model in rats so as to clarify the eventual interaction between these vitamins and the N-methyl-D-aspartate (NMDA) system.