Gas chromatography in the low concentration determination of nitrous oxide and volatile anaesthetics

Uyanık A.

Turkish Journal of Chemistry, vol.22, no.3, pp.267-271, 1998 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 3
  • Publication Date: 1998
  • Journal Name: Turkish Journal of Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.267-271
  • Keywords: Gas chromatography, Halothane, Isoflurane, Nitrous oxide
  • Ondokuz Mayıs University Affiliated: Yes


A previously reported single-column gas Chromatographic separation method was modified for dual-detection gas chromatography (TCD+FID) and evaluated for the low concentration analysis of volatile anaesthetics (halothane, isoflurane) and nitrous oxide. It was found that no serious problem occurs in the determination of volatile anaesthetics with FID (<10 ppm), but nitrous oxide introduces lack of sensitivity at lower concentrations with TCD (<40 ppm) in the described analysis method with a 0.25 ml sample loop.