POLYMORPHISM IN THE H-RAS PROTO-ONCOGENE IN CASES OF URINARY BLADDER CANCER

Tural Ş., Güneş S., Buyukalpelli R., Bagci H.

TURKISH JOURNAL OF UROLOGY, vol.32, no.1, pp.14-18, 2006 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 1
  • Publication Date: 2006
  • Journal Name: TURKISH JOURNAL OF UROLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.14-18
  • Keywords: Bladder Cancer, H-ras proto-oncogene, single nucleotide polymorphism
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Introduction: Ras proteins play role in signal transduction, cell division and differentiation. Ras protein is encoded by a gene located at 11p15.5 in human. The purpose of this study was to investigate the possible association of H-ras proto-oncogene T/C single nucleotide polymorphism at nucleotide sequence 81 with bladder cancer in Turkish population.