ANNALS OF SURGICAL TREATMENT AND RESEARCH, vol.98, no.2, pp.89-95, 2020 (SCI-Expanded)
Article / Article
ANNALS OF SURGICAL TREATMENT AND RESEARCH
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anastomotic leak, Colonic neoplasms, Hyperthermia, Oxaliplatin, Platelet-rich plasma, CYTOREDUCTIVE SURGERY, PERITONEAL CARCINOMATOSIS, COLONIC ANASTOMOSIS, CANCER, SURVIVAL, STOMA
Ondokuz Mayıs University Affiliated:
Purpose: Hyperthermic intraperitoneal chemotherapy (HIPEC) is a novel treatment option for peritoneal surface malignancies. Due to cytotoxic effects of chemotherapeutic agents, anastomosis healing can be impaired and lead to leakage rates higher than conventional intestinal surgery. In this experimental study, we aimed to investigate the effects of platelet-rich plasma (PRP) on colonic anastomosis in rats that received HIPEC with oxaliplatin.