Effect of EMLA Cream, Cold Spray, and Buzzy on Venipuncture Pain and Fear in Children: A Randomized Controlled Trial


Akdemir M. A., Ozdemir A.

JOURNAL OF PERIANESTHESIA NURSING, cilt.41, sa.4, ss.910-916, 2026 (SCI-Expanded, SSCI, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 4
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1016/j.jopan.2025.10.012
  • Dergi Adı: JOURNAL OF PERIANESTHESIA NURSING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, CINAHL, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.910-916
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Purpose: To investigate the impact of EMLA cream, cold spray, and Buzzy applied during venipuncture on the pain and fear levels of children 7 to 12 years of age. Design: Randomized controlled trial. Methods: This study with four parallel groups was conducted in a pediatric blood collection unit in eastern Turkiye. A total of 187 children were randomized into four groups: control (n = 48), EMLA (n = 46), cold spray (n = 47), and Buzzy (n = 46). The control group underwent a routine venipuncture. The specified method was used before venipuncture in the EMLA (60 minutes before the procedure), cold spray (for 5 seconds immediately before the procedure), and Buzzy (1 minute before the procedure) groups. A descriptive characteristics form, the Wong-Baker FACES Scale, the visual analog scale, and the Children's Fear Scale were used to collect the data. Findings: The venipuncture pain levels of children in the EMLA, cold spray, and Buzzy groups were lower than those in the control group (P < .05). The children in the EMLA group had less venipuncture pain than those in the cold spray and Buzzy groups (P < .05). Based on the children's self-assessment, the children in the cold spray group experienced less pain than those in the Buzzy group (P < .05). The children in the EMLA and cold spray groups had lower fear levels during venipuncture than those in the control and Buzzy groups (P < .05). Conclusions: EMLA, cold spray, and Buzzy were effective in reducing venipuncture pain, while EMLA and cold spray were effective in reducing venipuncture fear in 7-to 12-year-old children.