Human Papilloma Virus Attributable Head and Neck Cancer in the Sudan Assessed by p16<SUP>INK4A</SUP> Immunostaining
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, cilt.13, sa.12, ss.6083-6086, 2012 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 12
- Basım Tarihi: 2012
- Doi Numarası: 10.7314/apjcp.2012.13.12.6083
- Dergi Adı: ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.6083-6086
- Ondokuz Mayıs Üniversitesi Adresli: Hayır
Özet
Background: The aim of this study was to screen for human papillomavirus (HPV) infections in head and neck squamous cell carcinomas (HNSCCs) using P16 immunostaining. Materials and Methods: A retrospective study was performed on 150 samples from patients diagnosed with HNSCCs. HPV status was determined using p16(INK4A). Results: 31 of the 150 (20.7%) HNSCCs were HPV positive. Conclusions: A large proportion of HNSCCs in Sudan are associated with HPV infection. The fact that the prevalence of HPV is high among Sudanese patients with head and neck cancers (HNC) has obvious implications for vaccine therapy.