Acute immune thrombocytopenic purpura: A comparative study of very high oral doses of methylprednisolone and intravenously administered immune globulin
The Journal of Pediatrics, cilt.125, sa.6 PART 1, ss.1004-1007, 1994 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 125 Sayı: 6 PART 1
- Basım Tarihi: 1994
- Doi Numarası: 10.1016/s0022-3476(05)82024-4
- Dergi Adı: The Journal of Pediatrics
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.1004-1007
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
We compared very high doses of methylprednisolone with intravenously administered immune globulin for treatment of acute idiopathic thrombocytopenic purpura. Fifty-seven children were randomly assigned to receive the immune globulin preparation, 0.5 gm/kg per day for 5 consecutive days (n = 19), orally administered methylprednisolone, 30 mg/kg per day for 7 days (n = 19), or orally administered methylprednisolone, 50 mg/kg per day for 7 days (n = 19). There were no differences in the response of the platelet counts among the groups. We conclude that these two therapies were equally effective; choice between them may be made according to cost and therapy-related risks. (J PEDIATR 1994;125:1004-7). © 1994 Mosby, Inc. All rights reserved.