Today, the dynamic structure of art continues its course in the axis of the new pursuits of the artists, in parallel with the cultural transformations. It can be said that it will be difficult to grasp the phenomenon of art, when the relationship of “change”, which is one of the unchangeable features of art, with culture is not resolved. In the research, the interdisciplinary approaches of the artists in the post-digital process are evaluated with ideological-hegemonic-political elements and scientific technological developments. It is seen that new technologies, which are known to have an impact in cultural transformations, enable important expansions in the definition of art, in the perception of the artist, in the form and content of the artwork. In communication models, corporate transactions, socialization efforts, entertainment,in games, virtual experiences with screen interfaces preferred to reality are replaced by experiences in three-dimensional space perception with augmented reality technologies. There are developments in the field of artificial intelligence and superior human projects for human-machine collaboration are continuing. The boundaries between virtual-real and machine-human are tried to be melted. It is aimed to explain post-digital art in the relationship of cultural structure transformed with these fields of activity.