Presepsin (sCD14-ST) as a biomarker of sepsis in clinical practice and in emergency department: a mini review
LABORATORIUMSMEDIZIN-JOURNAL OF LABORATORY MEDICINE, vol.39, no.6, pp.367-372, 2015 (SCI-Expanded, Scopus)
- Publication Type: Article / Review
- Volume: 39 Issue: 6
- Publication Date: 2015
- Doi Number: 10.1515/labmed-2015-0072
- Journal Name: LABORATORIUMSMEDIZIN-JOURNAL OF LABORATORY MEDICINE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.367-372
- Keywords: diagnostic value, presepsin, sepsis, SOLUBLE CD14 SUBTYPE, DISSEMINATED INTRAVASCULAR COAGULATION, BACTERIAL-INFECTION, DIAGNOSTIC-ACCURACY, SEPTIC SHOCK, MULTICENTER, PREDICTION, MARKER, PROGNOSIS, SEVERITY
- Ondokuz Mayıs University Affiliated: Yes
Abstract
Presepsin is a 13-kDa protein that is a fragment of CD14 with truncated N-terminal, the receptor for lipopolysaccharide (LPS)/LPS-binding protein complexes. It is a novel marker being sought in many diseases such as sepsis, kidney failure, disseminated intravascular coagulation, etc. In this review, we aimed to clarify its utility in critical diseases and availability in critical care settings such as emergency departments and intensive care units.