Lack of correlation between vitamin D and alkaline phosphatase levels among Saudi population

Alsharif M. H. K., Noureddin M. A., Alharbi M. N. M., Alharbi F. S. F., Alhaddad A. T., Bin Ofisan S. S., ...Daha Fazla

MEDICAL SCIENCE, cilt.25, sa.107, ss.16-25, 2021 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 107
  • Basım Tarihi: 2021
  • Dergi Adı: MEDICAL SCIENCE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.16-25
  • Anahtar Kelimeler: Vitamin D, Alkaline phosphatase, Saudi population, DIAGNOSIS
  • Ondokuz Mayıs Üniversitesi Adresli: Hayır

Özet

Objective: The present study evaluated the correlation between Vitamin D and Alkaline phosphatase levels among the Saudi population. Methods: Blood samples of patients with a complaint of pain in various body parts and other clinical symptoms of Vitamin D deficiency were tested for the levels of Vitamin D and ALP. The analyzes were carried out using SPSS version 20.0 software. Results: Vitamin D and ALP levels of 460 patients were analyzed. The mean levels of Vitamin-D and ALP were found to be 22.03 +/- 13.5 and 89.02 +/- 44.9. About 356 patients (77.4%) out of 460 had Vit-D deficiency, whereas 421 patients (91.5%) out of 460 had ALP at normal ranges. From the analysis based on the nationality, Saudi 223 patients out of 280 showed vitamin D deficiency and 257 patients out of 280 had normal ALP levels. No correlation between serum ALP and vitamin D levels was observed (r = 0.05, p = 0.2). Conclusion: serum alkaline phosphatase cannot be considered as a useful marker to represent the Vitamin D deficiency among the population.