Effects of 5-Hydroxymethylfurfural on Pubertal Development of Female Wistar Rats

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Elmaogullari S., Kadan E., ANADOL E., Gökçeoğlu A., Cetinkaya S., Yarım G. F., ...More

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, vol.12, no.1, pp.79-85, 2020 (SCI-Expanded, Scopus, TRDizin)

  • Publication Type: Article / Article
  • Volume: 12 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.4274/jcrpe.galenos.2019.2019.0080
  • Journal Name: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.79-85
  • Keywords: Hydroxymethylfurfural, puberty, vaginal opening, anti-Mullerian hormone, rat, ANTI-MULLERIAN HORMONE, ABERRANT CRYPT FOCI, INHIBITING SUBSTANCE, ASSAY, METABOLITE, ESTRADIOL, EXPOSURE, OVARY
  • Open Archive Collection: AVESIS Open Access Collection
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Objective: 5-Hydroxymethylfurfural (HMF) is formed when sugars are heated in the presence of amino acids. HMF is naturally present in many foods. To investigate the toxic effects of HMF on the reproductive system of peripubertal rats.