Hemopressin increases penicillin-induced epileptiform activity in rats


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Aygun H., Arsian G., Sen E., Ayyıldız M., Agar E.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.121, no.1, pp.37-42, 2020 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 121 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.4149/bll_2020_006
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Page Numbers: pp.37-42
  • Keywords: cannabinoid, CB1, epilepsy, hemopressin, penicillin, receptor, CB1 CANNABINOID RECEPTOR, ENDOCANNABINOID SYSTEM, PEPTIDE, MODEL, ACTIVATION, MECHANISMS, LIGANDS, AGONIST, LEPTIN
  • Open Archive Collection: AVESIS Open Access Collection
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

OBJECTIVE: Hemopressin (Hp) is the first peptide ligand described for the CB1 cannabinoid receptor. Therefore, we aimed to investigate the effect of hemopressin on pencillin-induced epileptiform activity by using electrophysiological recording (ECoG) technique.