Evaluation of Extramedullary Plasmacytoma of the Larynx with Radiologic and Histopathological Findings Evaluación del plasmocitoma extramedular de laringe con hallazgos radiológicos e histopatológicos
Radiologia, vol.64, no.1, pp.69-73, 2022 (ESCI, Scopus)
- Publication Type: Article / Article
- Volume: 64 Issue: 1
- Publication Date: 2022
- Doi Number: 10.1016/j.rx.2020.07.006
- Journal Name: Radiologia
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, MEDLINE, DIALNET
- Page Numbers: pp.69-73
- Keywords: Computed tomography, Extramedullary, Larynx, Solitary plasmacytoma
- Ondokuz Mayıs University Affiliated: Yes
Abstract
Extramedullary plasmacytoma (EMP) is a plasma cell neoplasm of soft tissue without bone marrow involvement or other systemic characteristics of multiple myeloma. Approximately 80-90% of EMPs involve the head and neck region, especially in the nasal cavity, paranasal sinuses, tonsillar fossa, and oral cavity. An EMP of the larynx is extremely rare and is a locally destructive lesion without systemic spread. Clinical features vary depending on the tumor location. A diagnosis is established by histopathology, immunohistochemistry, and a systemic survey to exclude systemic plasma cell proliferative diseases. Extramedullary plasmacytomas are highly radiosensitive and radiotherapy is therefore used as a treatment. In this study, we report on a rare case of EMP of the larynx evaluated with computed tomography and present histopathologic findings for a 74-year-old female patient.