Evaluation of Extramedullary Plasmacytoma of the Larynx with Radiologic and Histopathological Findings Evaluación del plasmocitoma extramedular de laringe con hallazgos radiológicos e histopatológicos
Radiologia, cilt.64, sa.1, ss.69-73, 2022 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 64 Sayı: 1
- Basım Tarihi: 2022
- Doi Numarası: 10.1016/j.rx.2020.07.006
- Dergi Adı: Radiologia
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, MEDLINE, DIALNET
- Sayfa Sayıları: ss.69-73
- Anahtar Kelimeler: Computed tomography, Extramedullary, Larynx, Solitary plasmacytoma
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Extramedullary plasmacytoma (EMP) is a plasma cell neoplasm of soft tissue without bone marrow involvement or other systemic characteristics of multiple myeloma. Approximately 80-90% of EMPs involve the head and neck region, especially in the nasal cavity, paranasal sinuses, tonsillar fossa, and oral cavity. An EMP of the larynx is extremely rare and is a locally destructive lesion without systemic spread. Clinical features vary depending on the tumor location. A diagnosis is established by histopathology, immunohistochemistry, and a systemic survey to exclude systemic plasma cell proliferative diseases. Extramedullary plasmacytomas are highly radiosensitive and radiotherapy is therefore used as a treatment. In this study, we report on a rare case of EMP of the larynx evaluated with computed tomography and present histopathologic findings for a 74-year-old female patient.