The angiotensin converting enzyme I/D polymorphism in Turkish athletes and sedentary controls.
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové, cilt.47, sa.2, ss.133-136, 2004 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 47 Sayı: 2
- Basım Tarihi: 2004
- Doi Numarası: 10.14712/18059694.2018.79
- Dergi Adı: Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.133-136
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ondokuz Mayıs Üniversitesi Adresli: Hayır
Özet
The angiotensin converting enzyme (ACE) gene is located on human chromosome 17 expressing three genotypes within the intron 16 of the related gene structure. These genotypes are classified as I and D alleles which are termed as insertion and deletion, respectively. This study was carried out to identify possible relationships between the insertion/deletion (I/D) polymorphisms and athletic performance in Turkish athletes. To be able to determine these relationships, eighty healthy athletes and eighty healthy sedentary controls were genotyped for the ACE I/D polymorphism at gene level. According to the results obtained, we found significant difference on ACE I/D polymorphism in between athletes and healthy controls (x2 = 7.32, df = 2, P = 0.026). This result supports the association in ACE genotype in Turkish athletes, suggesting that this might be a genetic factor influencing the physical performance.