The angiotensin converting enzyme I/D polymorphism in Turkish athletes and sedentary controls.
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové, vol.47, no.2, pp.133-136, 2004 (Scopus)
- Publication Type: Article / Article
- Volume: 47 Issue: 2
- Publication Date: 2004
- Doi Number: 10.14712/18059694.2018.79
- Journal Name: Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové
- Journal Indexes: Scopus
- Page Numbers: pp.133-136
- Open Archive Collection: AVESIS Open Access Collection
- Ondokuz Mayıs University Affiliated: No
Abstract
The angiotensin converting enzyme (ACE) gene is located on human chromosome 17 expressing three genotypes within the intron 16 of the related gene structure. These genotypes are classified as I and D alleles which are termed as insertion and deletion, respectively. This study was carried out to identify possible relationships between the insertion/deletion (I/D) polymorphisms and athletic performance in Turkish athletes. To be able to determine these relationships, eighty healthy athletes and eighty healthy sedentary controls were genotyped for the ACE I/D polymorphism at gene level. According to the results obtained, we found significant difference on ACE I/D polymorphism in between athletes and healthy controls (x2 = 7.32, df = 2, P = 0.026). This result supports the association in ACE genotype in Turkish athletes, suggesting that this might be a genetic factor influencing the physical performance.