The Tp-e interval and Tp-e/QT ratio as markers of ventricular repolarization dispersion and atrial conduction heterogeneity following electrical injury: A retrospective case-control study

Yanik A., Ozgen E., Boyacı F., Akcay M., Şahin M. K.

JOURNAL OF ELECTROCARDIOLOGY, cilt.95, sa.March–April 2026, ss.1-7, 2026 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 95 Sayı: March–April 2026
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1016/j.jelectrocard.2026.154202
  • Dergi Adı: JOURNAL OF ELECTROCARDIOLOGY
  • Derginin Tarandığı İndeksler: Scopus, Science Citation Index Expanded (SCI-EXPANDED), CINAHL, EMBASE
  • Sayfa Sayıları: ss.1-7
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: Electrical injuries are a significant cause of cardiovascular morbidity and life-threatening arrhythmias. This study aimed to evaluate markers of ventricular repolarization dispersion and atrial conduction heterogeneity, specifically, the Tp-e interval, Tp-e/QT ratio, and P-wave dispersion, in patients presenting with electrical injury Methods: In this retrospective case-control study, 50 patients with electrical injury were compared with 59 age- and sex-matched healthy controls. Standard 12‑lead electrocardiograms were obtained for all participants. Key parameters, Tp-e interval, Tp-e/QT ratio, Tp-e/QTc ratio, and P-wave dispersion, were manually measured by two blinded cardiologists with excellent interobserver reliability. A subgroup analysis was also performed within the injury cohort based on troponin status Results: The Tp-e interval was significantly prolonged in the electrical injury group compared to controls (median 85.0 ms vs. 80.0 ms, p < 0.001). The Tp-e/QT ratio (0.24 vs. 0.21, p < 0.001), Tp-e/QTc ratio (0.20 vs. 0.19, p = 0.005), and P-wave dispersion (45.0 ms vs. 25.0 ms, p < 0.001) were also elevated in patients with electrical injury. Notably, no significant differences in these electrocardiographic parameters were observed between troponin-positive and troponin-negative subgroups Conclusion: Electrical injury is associated with significant acute abnormalities in ventricular repolarization and atrial conduction heterogeneity, independent of troponin elevation. The Tp-e interval, Tp-e/QT ratio, and P-wave dispersion may serve as potential electrocardiographic markers of arrhythmic risk in this population, though their prognostic utility requires validation in prospective studies