Patient reported voice handicap and auditory-perceptual voice assessment outcomes in patients with COVID-19
LOGOPEDICS PHONIATRICS VOCOLOGY, vol.48, no.2, pp.88-97, 2023 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 48 Issue: 2
- Publication Date: 2023
- Doi Number: 10.1080/14015439.2021.2011958
- Journal Name: LOGOPEDICS PHONIATRICS VOCOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, Communication & Mass Media Index, EMBASE, Linguistics & Language Behavior Abstracts, MEDLINE, Music Index
- Page Numbers: pp.88-97
- Keywords: COVID-19, dysphonia, auditory-perceptual assesment, voice handicap index, RELIABILITY, INFECTION
- Ondokuz Mayıs University Affiliated: Yes
Abstract
Purpose The purpose of this study is to compare patient-reported voice handicap and auditory-perceptual measures of voice between healthy individuals and COVID-19 patients, as well as to investigate the effect of clinical factors on voice quality. Methods COVID-19 patients (n = 138) and 90 healthy controls were included in the study. The Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) was used to grade voice samples based on overall severity, roughness, breathiness, strain, pitch, and loudness. The Voice Handicap Index-10 was completed by all participants (VHI-10). Physical (pVHI), emotional (eVHI) and functional (fVHI) subscores were calculated. Clinical data were collected (disease stage, CT grade, neutrophil/lymphocyte ratio, CRP, and symptoms). Results A statistically significant difference between patient and control groups in VHI-10 and CAPE-V scores was detected (p < 0.001). Except eVHI, total score and all subscale scores were higher in patients with COVID-19 as the pVHI was the most affected (eta(2) = 0.324) subscale. All scores of CAPE-V were significantly worse in patients with COVID-19 as highest impact of COVID-19 was on breathiness (eta(2) = 0.518). Pre-existing pulmonary comorbidity(,) dyspnoea and N/L was significantly associated with the VHI-10 overall score (beta(pc) = 4.27, beta(dyspnoea) = 5.69 and beta(nl) = 0.25). The overall severity of CAPE-V was significantly dependent on dyspnoea and pulmonary comorbidity (beta(dyspnoea) = 11.25, beta(pc) = 10.12). VHI >= 4 and CAPE-V overall severity >= 11 were good indicators of COVID-19 related dysphonia. Conclusions COVID-19 causes patient-reported voice handicap and deteriorates auditory-perceptual measures of voice. COVID-19 related voice impairment was mainly associated with the decreased respiratory capacity.