Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic hematopoietic stem cell transplantation for acute leukemia patients: A single center experience

GÖKER H., Ozdemir E., Uz B., BÜYÜKAŞIK Y., Turgut M., Serefhanoglu S., ...More

TRANSFUSION AND APHERESIS SCIENCE, vol.49, no.3, pp.590-599, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.1016/j.transci.2013.07.030
  • Journal Name: TRANSFUSION AND APHERESIS SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.590-599
  • Keywords: Reduced intensity conditioning regimen, Myeloablative conditioning regimen, Allogeneic hematopoietic stem cell transplantation, Graft-versus-host disease, ACUTE MYELOID-LEUKEMIA, ACUTE LYMPHOBLASTIC-LEUKEMIA, VERSUS-HOST-DISEASE, BONE-MARROW-TRANSPLANTATION, 1ST COMPLETE REMISSION, RISK MYELODYSPLASTIC SYNDROME, ACUTE MYELOBLASTIC-LEUKEMIA, ANTITHYMOCYTE GLOBULIN, SUSTAINED REMISSIONS, PREPARATIVE REGIMEN
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Due to the high transplant related morbidity and mortality (TRM), relatively younger acute leukemia patients that have a good performance status and no comorbidity are eligible for myeloablative conditioning (MAC) followed by allogeneic hematopoietic stem cell transplantation (allo-HSCT).