Examination of essential oil composition and fatty acids of Hypericum perforatum growing wild in Algeria


Roumaissa L., Saida C. H., Derbak L., Raniya N., Demirtaş İ., Hamdi B.

Brazilian Journal of Health Review, cilt.8, sa.1, ss.1-15, 2025 (Hakemli Dergi)

Özet

Hypericum perforatum L. belongs to Hypericaceae family is a rich source of secondary metabolites such as monoterpenes, sesquiterpenes, phloroglucinols (hyperforin and adhyperforin), naphthodiantrones derivatives (hypericin and pseudohypericin) and essential oil. The present research was performed for the first time to characterize the diversity in the chemical composition and fatty acids in essential oil of Hypericum perforatum harvested from Algeria. The flowering aerial parts of Hypericum perforatum were collected from south-west parts of Algeria and examined for essential oil components by GC-MS/MS and GC-FID/MS which yielded 0.26 %. The essential oil was characterized by a refractive index (1.228), a high acid value (3.5 mg KOH∙g), a saponification number of (120.49 mg KOH∙g), and ester index (122.32). Seventy constituents were identified by employing GC-MS/MS, Formic acid, undecyl ester (8.60 %), 2-Pinene (8.41 %), n-Pentadecanol (6.26 %), Caryophyllene oxide (4.16 %), β-Selinene (3.71 %) Linalool (3.25 %) and Citronellol (2.99%) considered as a main components, however, concerning the GC-FID/MS analysis, eight fatty acids founded and cis-10-Pentadecenoic acid (11.42 %), Heptadecanoic acid (3.46 %) and Lauric acid (2,16%) were the major components. The fluctuation between the results of Hypericum perforatum obtained in this study and prior reports demonstrate that the phytochemical composition of the essential oil is different for the same species attained at many cites. The quantitative analysis in the fatty acids revealed that essential oil of Hypericum perforatum contain a scarce amount of lipid content. The studies on Hypericum perforatum essential oil are still not sufficient to illustrate his usage as a dietary supplement or phytomedicine.