Effect of tacrolimus in the inner ear of rats

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Uysal F., Erbek S. S., Erbek S., Çulhaoğlu B.

CUKUROVA MEDICAL JOURNAL, vol.47, no.1, pp.128-133, 2022 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.17826/cumj.1030500
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.128-133
  • Keywords: Distortion-product otoacoustic emission, hearing loss, ototoxicity, tacrolimus, CALCINEURIN INHIBITORS, HEARING-LOSS
  • Ondokuz Mayıs University Affiliated: Yes


Purpose: Tacrolimus, an immunosuppressive agent, is used especially after organ transplantation. It has been asserted that tacrolimus has protective effects on the auditory system in some studies while it has negative effects in other studies. The purpose of our study is to investigate the effect of tacrolimus on the inner ear of the rats.