The value of immunoglobulin and complement levels in the early diagnosis of neonatal sepsis

KALAYCI, Ayhan; Adam, B.; Yilmazer, F.; Uysal, S.; Gürses, N.

doi:10.1111/j.1651-2227.1997.tb15187.x

The value of immunoglobulin and complement levels in the early diagnosis of neonatal sepsis

KALAYCI A. G., Adam B., Yilmazer F., Uysal S., Gürses N.

Acta Paediatrica, International Journal of Paediatrics, cilt.86, sa.9, ss.999-1002, 1997 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 86 Sayı: 9
Basım Tarihi: 1997
Doi Numarası: 10.1111/j.1651-2227.1997.tb15187.x
Dergi Adı: Acta Paediatrica, International Journal of Paediatrics
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.999-1002
Anahtar Kelimeler: Complement, Immunoglobulin, Neonatal sepsis
Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Serum IgG, IgG1, G2, G3, G4, IgM, C3c and C4 concentrations were measured in 24 term neonates with sepsis and 17 healthy normal neonates of similar age, sex and weight (control group). The serum IgG, IgG1, G2, G3, G4, IgM, C3c, and C4 levels were similar in the patients with sepsis and the control group (p > 0.05). In the neonates with sepsis, serum IgG, G1, G2, IgM and CA levels were not significantly different between the 1st and 10th days, while there were significant differences for IgG3, G4 and C3c (p < 0.05). We conclude that the serum levels of IgG, IgG1, G2, G3, G4, IgM, C3c and C4 concentrations are of no value for the early diagnosis of neonatal sepsis.