Effect of Age and Disease Duration on the Levodopa Response in Patients with Advanced Parkinson's Disease for Deep Brain Stimulation of the Subthalamic Nucleus

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AYGÜN D., Kocabıçak E., Yildiz M. O., Temel Y.

FRONTIERS IN NEUROLOGY, cilt.7, 2016 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7
  • Basım Tarihi: 2016
  • Doi Numarası: 10.3389/fneur.2016.00097
  • Dergi Adı: FRONTIERS IN NEUROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Parkinson's disease, deep brain stimulation, levodopa response, age, disease duration, subthalamic nucleus, MULTIPLE-SYSTEM ATROPHY, MOVEMENT-DISORDERS, DIAGNOSIS, CHALLENGE, CANDIDATES, ACCURACY, SUBTYPES
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: Deep brain stimulation (DBS) has become a preferred option for the treatment of motor symptoms in patients with advanced Parkinson's disease (PD). A good levodopa response (LR) is considered the most important criterion in determining the suitability of a patient for DBS. However, the effect of age and disease duration (DD) on the LR is still a subject of discussion.