2-Amino-4-(2-naphthyl)thiophene-3-carbonitrile
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, cilt.61, 2005 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 61
- Basım Tarihi: 2005
- Doi Numarası: 10.1107/s1600536805013425
- Dergi Adı: ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
A new type of thiophene derivative with potential pharmacological activity, viz. 2-amino-4-(2-naphthalyl) thiophene-3carbonitrile, C15H10N2S, has been prepared and studied by NMR and single-crystal X- ray diffraction techniques. The molecule contains two different groups, naphthalene and thiophene, which are nearly perpendicular to one another. In the crystal structure, a hydrogen bond, with a D center dot center dot center dot A distance of 3.033 (3) angstrom, is present between the amino substituent and the carbonitrile N atom of a symmetry-related molecule. The crystal structure also includes one C-H center dot center dot center dot pi interaction.