Typing of Candidemia Agents of Candida albicans Isolates by Molecular Methods and Investigation of SAP4 Gene Presence

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BİLGİN K., Birinci A., YILDIRIM T.

FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI, cilt.25, sa.3, ss.316-324, 2020 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5578/flora.69022
  • Dergi Adı: FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.316-324
  • Anahtar Kelimeler: Candida albicans, Pulsed field gel electrophoresis, Virulence factor, SECRETED ASPARTYL PROTEINASES, RELATEDNESS, BLOOD
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Introduction: In recent years, increasing infections due to fungi have drawn attention. Especially, Candida albicans is the most frequent infectious agent with its virulence factors. Furthermore, because C. albicans is a nosocomial infection agent, it can lead an increase in mortality and morbidity. In this study, it was aimed to genotype C. albicans strains that caused candidemia by molecular methods and to investigate one of the most important virulence factors, Secreted Aspartyl Proteinase 4 (SAP4).