Crystal structure and Hirshfeld surface analysis of 2-{[(E)-(3-cyclobutyl-1H-1,2,4-triazol-5-yl)imino]-methyl}phenol

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GÜMÜŞ M. K., ŞEN F., Kansiz S., DEGE N., Saif E.

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, cilt.77, ss.1267-1280, 2021 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 77
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1107/s2056989021011658
  • Dergi Adı: ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.1267-1280
  • Anahtar Kelimeler: crystal structure, cyclobutyl, triazole, salicylaldehyde, microwave-assisted synthesis, Hirshfeld surface
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

The title compound, C13H14N4O, was developed using the reaction of salicylaldehyde and 3-amino-5-cyclobutyl-1,2,4-triazole in ethanol under microwave irradiation. This eco-friendly microwave-promoted method proved to be efficient in the synthesis of 2-{[(E)-(3-cyclobutyl-1H-1,2,4-triazol-5-yl)imino]-methyl}phenol in good yields and purity. The title compound is a Schiff base that exists in the phenol-imine tautomeric form and adopts an E configuration. The three independent molecules in the asymmetric unit (A, B and C) are not planar, the cyclobutyl and the phenol-imine rings are twisted to each other making a dihedral angle of 67.8 (4)degrees in molecule A, 69.1 (2)degrees in molecule B and 89.1 (2)degrees in molecule C. In each molecule an intramolecular O-H center dot center dot center dot N hydrogen bond is present, forming an S(6) ring motif. A Hirshfeld surface analysis was performed to investigate the contributions of the different intermolecular contacts within the supramolecular structure. The major interactions are H center dot center dot center dot H (53%), C center dot center dot center dot H (19%) and N center dot center dot center dot H (17%) for molecule A, H center dot center dot center dot H (50%), N center dot center dot center dot H (20%) and C center dot center dot center dot H (20%) for molecule B and H center dot center dot center dot H (57%), C center dot center dot center dot H (14%) and N center dot center dot center dot H (13%) for molecule C.