Possible role of sildenafil in inhibiting rat vas deferens contractions by influencing the purinergic system

Bilge S. S., Kesim Y., Kurt M., Aksoz E., Celik S.

INTERNATIONAL JOURNAL OF UROLOGY, vol.12, no.9, pp.829-834, 2005 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 9
  • Publication Date: 2005
  • Doi Number: 10.1111/j.1442-2042.2005.01127.x
  • Journal Name: INTERNATIONAL JOURNAL OF UROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.829-834
  • Keywords: ejaculation, purinergic system, rat, sildenafil, vas deferens, P-2-PURINOCEPTOR ANTAGONISTS, CORPUS CAVERNOSUM, ECTO-NUCLEOTIDASES, SMOOTH-MUSCLE, EVANS BLUE, IN-VITRO, ATP, RELAXATION, SURAMIN, NORADRENALINE
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Aim: To evaluate the effect of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-selective type 5 phosphodiesterase, on isolated rat vas deferens and its connections with the purinergic system.