Possible role of sildenafil in inhibiting rat vas deferens contractions by influencing the purinergic system

Bilge S. S., Kesim Y., Kurt M., Aksoz E., Celik S.

INTERNATIONAL JOURNAL OF UROLOGY, cilt.12, sa.9, ss.829-834, 2005 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 9
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1442-2042.2005.01127.x
  • Dergi Adı: INTERNATIONAL JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.829-834
  • Anahtar Kelimeler: ejaculation, purinergic system, rat, sildenafil, vas deferens, P-2-PURINOCEPTOR ANTAGONISTS, CORPUS CAVERNOSUM, ECTO-NUCLEOTIDASES, SMOOTH-MUSCLE, EVANS BLUE, IN-VITRO, ATP, RELAXATION, SURAMIN, NORADRENALINE
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Aim: To evaluate the effect of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-selective type 5 phosphodiesterase, on isolated rat vas deferens and its connections with the purinergic system.