Effects of Isotretinoin on Serum Creatine Phosphokinase Levels in Patients with Acne Vulgaris

Oezden M. G., Karlikaya G., Bek Y., Mutlu N.

TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, vol.42, no.2, pp.56-59, 2008 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 2
  • Publication Date: 2008
  • Journal Name: TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.56-59
  • Keywords: Acne vulgaris, creatine phosphokinase, isotretinoin, myopathy, RHABDOMYOLYSIS, VALUES
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Background and Design: It has been known that isotretinoin may cause rabdomyolysis besides its many side affects. The purpose of our study was to evaluate the effect of isotretinoin therapy with a cumulative dose of 120 mg/kg on serum creatine phosphokinase levels and muscle physiology in patients with acne vulgaris.