The use of non-steroidal anti-inflammatory drugs diseases

Terzi M., Altun G., Şen S., Kocaman A., KAPLAN A. A., Yurt K. K., ...More

JOURNAL OF CHEMICAL NEUROANATOMY, vol.87, pp.12-24, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 87
  • Publication Date: 2018
  • Doi Number: 10.1016/j.jchemneu.2017.03.003
  • Journal Name: JOURNAL OF CHEMICAL NEUROANATOMY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.12-24
  • Keywords: Non-steroidal anti-inflammatory drugs, Cyclooxygenase inhibition, Prostaglandins, Neuroinflammation, Neurodegeneration, Neuroinflammation, AMYOTROPHIC-LATERAL-SCLEROSIS, PARKINSONS-DISEASE, ALZHEIMERS-DISEASE, MULTIPLE-SCLEROSIS, NITRIC-OXIDE, RISK, BRAIN, CYCLOOXYGENASE, ASPIRIN, NSAID
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) have been in use for many years and constitute a large part of prescriptions issued in daily practice. Although NSAIDs are used for many diseases in neurology, they have also been tested as a new therapeutic option for various other diseases. While their effects on headache and cerebrovascular diseases are well known, little is known about their impact on neurodegenerative diseases. This review discusses the use, effects and safety of NSAIDs in neurological diseases. (C) 2017 Published by Elsevier B.V.