Procedure Guideline for Scintigraphic Imaging in Cardiac Transthyretin Amyloidosis Kardiyak Transtiretin Amiloidozu Değerlendirilmesinde Sintigrafik Görüntüleme Kılavuzu

ÖZDEMİR E., Tosun F., Altun G. D., DEMİR H., ÖZDEMİR S., Şen F.

Nuclear Medicine Seminars, vol.6, no.2, pp.190-197, 2020 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.4274/nts.galenos.2020.0013
  • Journal Name: Nuclear Medicine Seminars
  • Journal Indexes: Scopus, Directory of Open Access Journals
  • Page Numbers: pp.190-197
  • Keywords: Cardiac amyloidosis, Scintigraphy, Tc-99m pyrophosphate
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Amyloidosis is a multisystem disease that results from extracellular deposition of amyloid fibriles in tissue and cardiac involvement may be seen. Cardiac amyloidosis is a rare and mostly underdiagnosed cause of heart failure. Several types of amyloid can infiltrate the myocardium. Diagnosis is usually made with endomyocardial biopsy. Scintigraphic imaging with Technetium (Tc-99m) labelled biphosponates may facilitate early detection of cardiac involvement and distinguish various forms of cardiac amyloidosis. The aim of this guideline is to assist nuclear medicine physicians in recommending, imaging, reporting and interpreting the results of scintigraphy with Tc-99m labelled bone radiopharmaceuticals for the evaluation of transthyretin cardiac amyloidosis.