Evaluation of laboratory parameters in inflammatory myositis

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Turkish Journal of Clinics and Laboratory, vol.12, no.3, pp.255-259, 2021 (Peer-Reviewed Journal) identifier


Aim: Polymyositis (PM) and dermatomyositis (DM) are the two most common forms of idiopathic inflammatory myositis (IIM) and they are generally rare diseases. We evaluate the relationship of C-reactive protein (CRP)/albumin ratio (CAR), neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio and other inflammatory markers with IIM. Material and Methods: 30 patients and 30 healthy volunteers aged >18 years were included. Demographic data such as age, gender were recorded. CRP, erythrocyte sedimentation rate (ESR), albumin values, leukocyte, neutrophil, lymphocyte, platelet counts were determined. Results: The median (IQR) age of the patients and healthy volunteers were 46 (38-60) years and 45 (42-52) years, respectively. 50% of the patients had a diagnosis of DM and 50% of them had a diagnosis of PM, and the median (IQR) duration of disease was 4 (0.5-13) years. The median value of CAR was 3.6 (1.0-5.1) in the patient group and 0.3 (0.1-0.6) in the control group; the NLR was 3.4 (2.3-4.4) in the patient group, 1.8 (1.6-2.1) in the control group; PLR was 223 (157-249) in the patient group, 107 (100-125) in the control group and CAR, NLR, and PLR values between the groups were significantly different (p