Increased Laterality of the Thalamus in Children and Adolescents with Asperger's Disorder: An MRI and Proton Spectroscopy Study


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SAY G. N., Şahin B., Aslan K., Akbas S., İncesu L., Ceyhan M.

PSYCHIATRY INVESTIGATION, vol.11, no.3, pp.237-242, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.4306/pi.2014.11.3.237
  • Journal Name: PSYCHIATRY INVESTIGATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.237-242
  • Keywords: Asperger, Autism, Thalamus, Laterality, Language, Children, AUTISM SPECTRUM DISORDERS, BRAIN SIZE, VOLUME, IMAGES
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Objective Thalamic abnormalities have been reported in people with pervasive developmental disorders (PDD) including Asperger's Disorder (ASP). The aim of the present study was to compare the volume and volume fraction of the thalamus and the metabolite concentrations in children and adolescents with ASP using the magnetic resonance imaging and proton magnetic resonance spectroscopy. Additionally, the relationships between thalamic abnormalities and clinical features were examined.