Analysis of the Protective Biochemical and Pathologic Effects of Aminoguanidine on an Experimental Aspiration Pneumonitis Model Induced by Bile Acids

Karli R., Alacam H., Duran L., Alici O., Katı C., Karli A., ...More

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, vol.73, no.6, pp.207-219, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 73 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1016/j.curtheres.2012.08.002
  • Journal Name: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.207-219
  • Keywords: aminoguanidine, aspiration pneumonitis, bile acids, CC-16, gastroesophageal reflux, LUNG INJURY, PULMONARY ASPIRATION, REFLUX, SERUM, ASSAY
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

BACKGROUND: Gastroesophageal reflux (GER) is a common clinical pathology detected in childhood. Bile acids (BAs) are present in reflux and cause various pathologies in the esophagus, the larynx, and the lungs.