Non-A, non-B/C hepatitis Non-A, non-B/C hepatiti.

Durupinar B.

Mikrobiyoloji bülteni, vol.27, no.3, pp.259-265, 1993 (Scopus) identifier identifier

  • Publication Type: Article / Review
  • Volume: 27 Issue: 3
  • Publication Date: 1993
  • Journal Name: Mikrobiyoloji bülteni
  • Journal Indexes: Scopus
  • Page Numbers: pp.259-265
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

A recombinant immunoscreening approach was used to clone and identified the genome of the non-A, non-B hepatitis virus. This agent is a positive-stranded RNA virus that appears to be distantly related to the flaviviridae family. A recombinant viral antigen (C100-3) was used to develop a "capture" assay for circulating antibody. Data obtained using this assay indicate that this agent, termed the Hepatitis C virus (HCV), is the major cause of post-transfusion, community-acquired and cryptogenic, NANB. HCV is associated with the development of hepatocellular carcinoma and possibly, other liver diseases. In this article the characteristic of Hepatitis C virus were discussed.