Protective Effect of Spirulina on Cisplatin-Induced Ototoxicity: A Functional and Histopathological Study

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Tahir E., Buyuklu A. F., Ocal F. C. A., GÜRGEN S. G., Sarsmaz H. Y.

B-ENT, vol.18, no.1, pp.34-43, 2022 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 18 Issue: 1
• Publication Date: 2022
• Doi Number: 10.5152/b-ent.2022.21666
• Journal Name: B-ENT
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.34-43
• Keywords: cisplatin, ototoxicity, spirulina, antioxidants, hearing loss, auditory brain stem evoked responses, distortion product otoacoustic emissions, apoptosis, COCHLEA, HEARING
• Ondokuz Mayıs University Affiliated: Yes

Abstract

Objective: The purpose of this study was to evaluate the protective effect of an antioxidant and anti-inflammatory agent, "spirulina," against cisplatin-induced ototoxicity in rats.