Protective Effect of Spirulina on Cisplatin-Induced Ototoxicity: A Functional and Histopathological Study

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Tahir E., Buyuklu A. F., Ocal F. C. A., GÜRGEN S. G., Sarsmaz H. Y.

B-ENT, cilt.18, sa.1, ss.34-43, 2022 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 18 Sayı: 1
• Basım Tarihi: 2022
• Doi Numarası: 10.5152/b-ent.2022.21666
• Dergi Adı: B-ENT
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.34-43
• Anahtar Kelimeler: cisplatin, ototoxicity, spirulina, antioxidants, hearing loss, auditory brain stem evoked responses, distortion product otoacoustic emissions, apoptosis, COCHLEA, HEARING
• Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objective: The purpose of this study was to evaluate the protective effect of an antioxidant and anti-inflammatory agent, "spirulina," against cisplatin-induced ototoxicity in rats.