Cardioprotective effect of aminoguanidine in combination with steroid therapy after blunt chest trauma

Creative Commons License

Duran L., Guzel A., Akdemir H. U., Demir F., Karadeniz C., Alacam H., ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.115, no.9, pp.538-543, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 115 Issue: 9
  • Publication Date: 2014
  • Doi Number: 10.4149/bll_2014_104
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.538-543
  • Keywords: cardiac contusion, blunt chest trauma, iNOS, Bcl-2, methylprednisolone, aminoguanidine, CARDIAC TROPONIN-T, MYOCARDIAL-INFARCTION, LUNG CONTUSION, INJURY, ISCHEMIA, REPERFUSION, RATS, METHYLPREDNISOLONE, MODEL, INFLAMMATION
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Background: Cardiac contusion is an important cause of mortality after blunt chest trauma (BCT). The aim of this study was to investigate the therapeutic efficacy of the usage of aminoguanidine (AG), in myocardial damage occurring after BCT, alone and in combination with methylprednisolone (MP).