Role of miR-6814-5p for the formation of T5, a heparanase variant, in renal cell carcinoma
CUKUROVA MEDICAL JOURNAL, cilt.46, sa.4, ss.1532-1536, 2021 (ESCI, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 46 Sayı: 4
- Basım Tarihi: 2021
- Doi Numarası: 10.17826/cumj.984271
- Dergi Adı: CUKUROVA MEDICAL JOURNAL
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.1532-1536
- Anahtar Kelimeler: Renal cell carcinoma, heparanase, gene expression regulation, miR-6814-5p, PREDICTION
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Purpose: The aim of this study is to investigate whether the overexpression of human heparanase protein (HPSE) alternative variant protein called T5 is caused by increased expression of miR-6814-5p in human renal cell carcinoma (RCC) cases. In addition, the possible correlation between the clinical parameters of RCC cases and the expression levels of T5 and miR-6814-5p was evaluated.