Ameliorative effect of Leflunomide on lung injury following an aspiration

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Yilmaz M. Z., Torun A. C., Guzel A., Murat N., Okuyucu A., Yilmaz N., ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.116, no.3, pp.177-183, 2015 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 116 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.4149/bll_2015_036
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.177-183
  • Keywords: aspiration, lung injury, Leflunomide, iNOS, oxidative markers, RESPIRATORY-DISTRESS-SYNDROME, OXIDE SYNTHASE INHIBITOR, NITRIC-OXIDE, PULMONARY ASPIRATION, GASTROINTESTINAL DECONTAMINATION, ENTERAL SOLUTIONS, DISEASE, RATS, INFLAMMATION, VENTILATION
  • Open Archive Collection: AVESIS Open Access Collection
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Background: We aimed to investigate the therapeutic effectiveness of leflunomide (LEF) in lung injury after an aspiration of unknown pathophysiology.