Garcinia kola aqueous suspension prevents cerebellar neurodegeneration in long-term diabetic rat a type 1 diabetes mellitus model

Farahna, Mohammed; Etet, Paul; Osman, Sayed; Yurt, Kiymet; Amir, Naheed; Vecchio, Lorella; Aydin, Ismsu; Aldebasi, Yousef; Sheikh, Azimullah; Chijuka, John; Kaplan, Süleyman; Adem, Abdu

doi:10.1016/j.jep.2016.11.001

Garcinia kola aqueous suspension prevents cerebellar neurodegeneration in long-term diabetic rat a type 1 diabetes mellitus model

Copy For Citation

Farahna M., Etet P. F. S., Osman S. Y., Yurt K. K., Amir N., Vecchio L., ...More

JOURNAL OF ETHNOPHARMACOLOGY, vol.195, pp.159-165, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 195
Publication Date: 2017
Doi Number: 10.1016/j.jep.2016.11.001
Journal Name: JOURNAL OF ETHNOPHARMACOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.159-165
Keywords: Garcinia kola, Neuroprotection, Purkinje cell, Type 1 diabetes mellitus, Ataxia, Medicinal plant, MHZ ELECTROMAGNETIC-FIELD, BIFLAVONOID COMPLEX, AZADIRACHTA-INDICA, PRENATAL EXPOSURE, GLYCEMIC CONTROL, KOLAVIRON, TRANSPLANTATION, HIPPOCAMPUS, DYSFUNCTION, APOPTOSIS
Ondokuz Mayıs University Affiliated: Yes

Abstract

Ethnopharmacological relevance: The development of compounds able to improve metabolic syndrome and mitigate complications caused by inappropriate glycemic control in type 1 diabetes mellitus is challenging. The medicinal plant with established hypoglycemic properties Garcinia kola Heckel might have the potential to mitigate diabetes mellitus metabolic syndrome and complications.