Does thiol/disulfide homeostasis affect the number of metaphase 2 oocyte in the treatment of in vitro fertilization?
FUTURE SCIENCE OA, cilt.6, sa.2, 2020 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 6 Sayı: 2
- Basım Tarihi: 2020
- Doi Numarası: 10.2144/fsoa-2019-0132
- Dergi Adı: FUTURE SCIENCE OA
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
- Anahtar Kelimeler: antioxidants, embryo, in vitro fertilization success, infertility, metaphase 2, oocyte maturation, oxidative stress, pregnancy, serum, thiol, disulfide homeostasis, OXIDATIVE STRESS, MARKER, THIOLS
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Aim: To investigate the effect of thiol/disulfide homeostasis on the number of oocytes retrieved and metaphase 2 (M2) oocytes in patients undergoing in vitro fertilization. Method: A prospective study of 94 patients who were admitted to the in vitro fertilization clinic was conducted. Serum samples were taken on the oocyte pick-up day and kept until the analysis. Thiol and disulfide were measured in order to evaluate the total thiol/disulfide. Results: A statistically significant correlation was observed between disulfide and M2. Conclusion: This study provides an inexpensive and noninvasive method to measure oxidative stress, and suggests that there is a positive correlation between the number of M2 and disulfide, resulting in low-impact oxidative stress.