Low dose dopamine prevents end organ damage in experimentally induced pancreatitis

KAYA E., Arslan A., Aliyazicioglu Y., Guven H., Aydin O., Ozkan K.

HEPATO-GASTROENTEROLOGY, vol.52, no.64, pp.1250-1254, 2005 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 64
  • Publication Date: 2005
  • Journal Name: HEPATO-GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.1250-1254
  • Keywords: pancreatitis, dopamine, lactated ringer, myeloperoxicase activity, ACUTE LUNG INJURY, HEMORRHAGIC-PANCREATITIS, MICROCIRCULATORY IMPAIRMENT, BASE DEFICIT, MODEL, RAT, PATHOGENESIS, CYTOKINES, SEVERITY, THERAPY
  • Ondokuz Mayıs University Affiliated: No

Abstract

Background/Aims: End organ damage due to microcirculatory failure plays an important role in the pathogenesis of acute pancreatitis (AP). The aim of this study was to investigate whether dopamine, a vasoactive agent, is beneficial in the prevention of local and systemic injury in acute pancreatitis.