A case of acetaminophen (paracetamol) causing renal failure without liver damage in a child and review of literature
RENAL FAILURE, cilt.32, sa.9, ss.1125-1127, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 32 Sayı: 9
- Basım Tarihi: 2010
- Doi Numarası: 10.3109/0886022x.2010.509830
- Dergi Adı: RENAL FAILURE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1125-1127
- Anahtar Kelimeler: children, acetaminophen, renal failure, pathophysiology, nephrotoxicity
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Acetaminophen (paracetamol) is a widely used drug and known as a safety antipyretic and analgesic drug in childhood. Acetaminophen-associated liver damage is more recognized than kidney damage. Nephrotoxicity and hepatotoxicity can be seen together after acetaminophen overdose, but renal damage without liver damage is a rarely seen entity in all age groups being reported more rarely in childhood. We present here a 16-year-old girl with renal failure without liver damage because of acetaminophen toxicity and a review of literature for pathophysiological mechanisms, clinical course, treatment, and outcome.